Cancer

Cancer genomics is the study of the totality of DNA sequence and gene expression differences between tumour cells and normal host cells. Genomic data is increasingly used alongside information about the morphology of a tumour to inform diagnosis, treatment selection and management of the patient and their family.

Hereditary Cancer

Hereditary cancer syndromes are genetic disorders that are passed down from parents to children. These genetic disorders can put you at a higher risk of developing certain cancers. Inherited gene mutations can indicate increased risk for some cancers including breast, ovarian, colon, uterine, prostate, stomach, pancreatic, melanoma, or other rare cancers.

You should be screened for a hereditary cancer syndrome if

• Multiple close relatives are affected by cancer
• Multiple cancers occur in one person
• Cancer is diagnosed at a young age (younger than 45 years of age)
• Diagnosis is made of certain cancers such as colon, pancreas, ovary or endometrium.
• Genetic testing for another disorder reveals an unsuspected mutation that causes a hereditary syndrome.

Hereditary caner panel covers large number of cancer-associated genes. Gene in this panel has been selected based on its risk potential in the development of one or more of the following cancers: breast, ovarian, colorectal, gastric, thyroid, endometrial, pancreatic, melanoma, renal, and prostate, among others.